The Analysis Study Comparison of the Efficacy and Safety of Ciprofol Versus Propofol for Anesthesia Induction in Adult Patients Undergoing Elective Surgeries : A Comprehensive Systematic Review

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Shalmaa Larasati Pratiwi
Daniel Setiawan Nathan
Fajar Nurochman Sidik

Abstract

Background: This study aims to compare the efficacy and safety of ciprofol versus propofol for anesthesia induction in adult patients undergoing elective surgeries. Methods: Following PRISMA 2020 guidelines, this systematic review focused exclusively on full-text articles published in English between 2014 and 2024. Result: The study conducted a comprehensive review of over 100 publications sourced from reputable databases, including ScienceDirect, SagePub, and PubMed. Following an initial screening, eight publications were identified as warranting more in-depth analysis. Consequently, a thorough review of these selected studies was performed to ensure a detailed and rigorous evaluation. Conclusion: Ciprofol shows potential advantages over propofol for induction, including deeper anesthesia, lower incidence of hypotension, and reduced injection-site pain. However, further large-scale studies are needed to definitively determine if ciprofol is superior to propofol.

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