Association of Levels of Physical Activity With Risk of Parkinson Disease

Abstract

Background: The reviewed literature collectively underscores the significant association between levels of physical activity (PA) and the risk of Parkinson's disease (PD), illustrating both the neuroprotective effects of exercise and its role in enhancing the quality of life for those affected by this condition. Literature Review: Subsequent reviews, such as that by Lauzé et al. (Lauzé et al., 2016), build on this understanding by providing a nuanced perspective on the impact of PA on clinical symptoms and psychosocial aspects of life for PD patients. While benefits are evident, the variability in outcomes suggests that specific exercise modalities and individualized programs may be essential for maximizing efficacy. Bhalsing et al. (S. Bhalsing et al., 2018) further contextualize the importance of PA by discussing its role in preventing chronic diseases and its potential to delay disease progression, emphasizing the biological mechanisms that underpin these benefits. Research focusing on early-stage PD, such as that by Mantri et al. (Mantri et al., 2018), reveals a concerning trend: many individuals with early PD do not meet recommended activity levels, highlighting the need for targeted interventions. This aligns with findings from Lovegrove (Lovegrove, 2019), which identify barriers to sustained engagement in PA, underscoring the importance of addressing both personal and contextual factors to encourage exercise adherence among PD patients. Conclusion: In conclusion, the reviewed articles collectively advocate for the integration of physical activity into PD management strategies. They highlight the multifaceted benefits of exercise, the necessity for tailored interventions, and the importance of promoting PA from early stages of the disease. As the body of literature expands, it becomes increasingly clear that physical activity should be a fundamental aspect of both preventive and therapeutic approaches to Parkinson's disease.