The Analysis Study of Association Between Skin Microbiome and Acne: A Comprehensive Systematic Review

Abstract

Background: Acne vulgaris, more commonly referred to as acne, is a prevalent dermatological condition affecting individuals across a broad spectrum of ages, ethnicities, and geographical region. The skin microbiome, composed of diverse microbial communities, plays a crucial role in maintaining skin health. Methods: Following PRISMA 2020 guidelines, this systematic review focused exclusively on full-text articles published in English between 2014 and 2024. Result: The study conducted a comprehensive review of over 100 publications sourced from reputable databases, including ScienceDirect, SagePub, and PubMed. Following an initial screening, eight publications were identified as warranting more in-depth analysis. Consequently, a thorough review of these selected studies was performed to ensure a detailed and rigorous evaluation. Conclusion: The cutaneous microbiome plays a pivotal role in acne pathogenesis, with microbial diversity and species interactions influencing skin health and inflammation. Current treatments, while effective, may alter the microbiome in varying ways, highlighting the need for more targeted approaches. Emerging research on microbiome-based therapies, including probiotics and non-pathogenic bacterial strains, offers promising avenues for improving acne management.