The Analysis Study of Outcomes of Regenerative Endodontic Treatment for Immature Permanent Teeth Experiencing Pulpal Necrosis : A Comprehensive Systematic Review

Abstract

Background: The primary goal of non-surgical root canal therapy is to preserve the natural dentition, a challenge that becomes more complex when dealing with younger patients who have immature permanent teeth affected by pulpal necrosis. The aim of this systematic review is to evaluate the effectiveness of regenerative endodontic therapy (RET) in treating immature permanent teeth with pulpal necrosis. Methods: Following PRISMA 2020 guidelines, this systematic review focused exclusively on full-text articles published in English between 2014 and 2024. Result: The study conducted a comprehensive review of over 100 publications sourced from reputable databases, including ScienceDirect, SagePub, and PubMed. Following an initial screening, eight publications were identified as warranting more in-depth analysis. Consequently, a thorough review of these selected studies was performed to ensure a detailed and rigorous evaluation. Conclusion: RET has shown promising success in treating immature permanent teeth with pulpal necrosis, achieving high rates of primary outcomes and fostering continued root development.