Association of Use of Omega-3 Polyunsaturated Fatty Acids With Changes in Severity of Anxiety Symptoms

Abstract

Background: The exploration of omega-3 polyunsaturated fatty acids (PUFAs) and their potential association with anxiety symptoms has garnered increasing attention in the scientific community, as reflected in the literature spanning from 2007 to 2021. Literature Review: The review by (Bozzatello et al., 2019) provided a deeper understanding of the biochemical pathways involved in the anxiolytic effects of omega-3s, particularly focusing on interleukin-6, BDNF, and cortisol modulation. Their findings indicated a modest anxiolytic effect, particularly in neuropsychiatric disorders, while also acknowledging the need for more rigorous research specifically targeting anxiety disorders. (Fatemi et al., 2020) examined the dietary quality of fats and their relationship with anxiety, suggesting that a lower intake of omega-3s correlates with increased anxiety symptoms. This observation aligns with the findings of (Aucoin et al., 2021), who emphasized the role of inflammation and dietary composition in anxiety management. Their review underscored the protective benefits of omega-3-rich diets compared to other dietary fats, reinforcing the importance of nutritional strategies in addressing anxiety symptoms. Conclusion: In conclusion, the collective body of literature indicates that omega-3 PUFAs may have a beneficial role in managing anxiety symptoms, primarily through their anti-inflammatory effects and influence on neurotransmitter function. However, the limitations of current research, including small sample sizes and methodological inconsistencies, highlight the necessity for more rigorous and targeted studies. Future research should focus on well-defined clinical populations to better understand the efficacy and mechanisms of omega-3 supplementation in anxiety disorders.