The Analysis Study of Breast Cancer Clinicopathological Characteristics : A Comprehensive Systematic Review

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Rizky Cyntia Simamora
Ariyosep Siregar
Daniel Setiawan Nathan

Abstract

Background: Breast cancer (BC) is the most frequently diagnosed cancer globally, with over 2 million new cases reported in 2020. This study aims to provide a comprehensive systematic review regarding the clinicopathological features of breast cancer. Methods: Following PRISMA 2020 guidelines, this systematic review focused exclusively on full-text articles published in English between 2014 and 2024. Result: The study conducted a comprehensive review of over 100 publications sourced from reputable databases, including ScienceDirect, SagePub, and PubMed. Following an initial screening, eight publications were identified as warranting more in-depth analysis. Consequently, a thorough review of these selected studies was performed to ensure a detailed and rigorous evaluation. Conclusion: Breast cancer patients in developing countries are diagnosed younger, with more advanced stages and aggressive subtypes. Tailored screening and early detection programs, considering the younger age profile, are needed to improve diagnosis, outcomes, and reduce the healthcare system's burden.

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